Rs7250581

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is asnp
is mentioned by
dbSNPrs7250581
hapmaprs7250581
hgdprs7250581
ensemblrs7250581
gopubmedrs7250581
scholarrs7250581
googlers7250581
pharmgkbrs7250581
hgvbaseg2prs7250581
medrefsnprs7250581
23andMers7250581
SNP Nexus

Chromosome19
Orientationplus
Position34756236
GenotypeEffect
rs7250581(G;G)1.4x risk
rs7250581(A;G)normal
rs7250581(A;A)normal


Genotypes Magnitude Summary
Rs7250581(A;A) normal
Rs7250581(A;G) 00 normal
Rs7250581(G;G) 1.4x risk

rs7250581 has been reported in a large study to be associated with heart disease, in particular, coronary artery disease.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.06 (CI 0.79-1.43), and for homozygotes, 1.40 (CI 1.05-1.86). [PMID 17554300]

? (A;A) (A;G) (G;G)


[PMID 19955471] Genetic Variants Identified in a European Genome-Wide Association Study That Were Found to Predict Incident Coronary Heart Disease in the Atherosclerosis Risk in Communities Study