From SNPedia
| Geno
|
Mag
|
Summary
|
| (C;C)
|
0
|
normal
|
| (C;T)
|
|
1.3x increased risk of death if diagnosed with breast cancer
|
| (T;T)
|
|
>1.3x increased risk of death if diagnosed with breast cancer
|
| ? | (C;C) (C;T) (T;T) | 28 |
|---|
 |
Two SNPs associated with the antioxidant GPX4 gene, rs713041 and rs757229, are both somewhat correlated (r2=0.61) and are associated with all-cause mortality in breast cancer.
The rs713041(T) allele is associated with an increased risk of death following breast cancer diagnosis, with a hazard ratio of 1.27 per rare allele (CI: 1.13-11.43, p=0.0041).[PMID 17634480]
[PMID 20378690] Genetic variants in selenoprotein genes increase risk of colorectal cancer
[PMID 21733339] SNP and mRNA expression for glutathione peroxidase 4 in Kashin-Beck disease
