Rs7017300
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs7017300 |
| hapmap | rs7017300 |
| hgdp | rs7017300 |
| ensembl | rs7017300 |
| gopubmed | rs7017300 |
| scholar | rs7017300 |
| rs7017300 | |
| pharmgkb | rs7017300 |
| hgvbaseg2p | rs7017300 |
| medrefsnp | rs7017300 |
| 23andMe | rs7017300 |
| SNP Nexus |
| Chromosome | 8 |
| Orientation | plus |
| Position | 128594449 |
| Genotype | Effect |
|---|---|
| rs7017300(C;C) | 1.7x increased risk for prostate cancer |
| rs7017300(A;C) | 1.7x increased risk for prostate cancer |
| rs7017300(A;A) | normal risk |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs7017300(A;A) | 00 | normal risk |
| Rs7017300(A;C) | 1.7x increased risk for prostate cancer | |
| Rs7017300(C;C) | 1.7x increased risk for prostate cancer |
rs7017300 is one of 4 tightly linked SNPs in the "locus 1" region of 8q24 chromosomal region, which has been linked in several studies to prostate cancer, initially through rs1447295.[PMID 17925536]
In a study of 1,563 patients of European ancestry, the odds ratio for prostate cancer associated with risk genotypes of locus 1 were reported as 1.70 (CI: 1.39-2.07). Two other regions of chromosome 8q24 were also studied.[PMID 17925536]
| ? | (A;A) (A;C) (C;C) |
|---|---|
|
| |
