Rs6908425

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is asnp
is mentioned by
dbSNPrs6908425
hapmaprs6908425
hgdprs6908425
ensemblrs6908425
gopubmedrs6908425
scholarrs6908425
googlers6908425
pharmgkbrs6908425
hgvbaseg2prs6908425
medrefsnprs6908425
23andMers6908425
SNP Nexus

GeneCDKAL1
Chromosome6
Orientationplus
Position20836709
GenotypeEffect
rs6908425(C;C)1.9x risk
rs6908425(C;T)1.6x risk
rs6908425(T;T)normal


Genotypes Magnitude Summary
Rs6908425(A;A) 00
Rs6908425(C;C) 1.9x risk
Rs6908425(C;T) 1.6x risk
Rs6908425(T;T) 00 normal
rs6908425 has been reported in a large study to be associated with Crohn's disease.

The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 1.63 (CI 1.38-2.25), and for homozygotes, 1.95 (CI 1.43-2.67). [PMID 17554300]

? (C;C) (C;T) (T;T)


[PMID 18923449] Further genetic evidence for three psoriasis-risk genes: ADAM33, CDKAL1, and PTPN22

GWAS snp
PMID [PMID 18587394]
Trait Crohn's disease
Title Genome-wide assocation defines more than 30 distinct susceptibility loci for Crohn's disease
Risk Allele C
P-val 8.9999999999999999E-10
Odds Ratio 1.21 [NR]


[PMID 19587699] Differential contribution of CDKAL1 variants to psoriasis, Crohn's disease and type II diabetes