Rs6832769

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dbSNPrs6832769
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SNP Nexus

SNPshotrs6832769
SNPdbers6832769
MSV3drs6832769
GeneCLOCK
Chromosome4
Orientationplus
Position56298194
ReferenceGRCh37 37.1/131
Max Magnitude
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? (A;A) (A;G) (G;G) 28

[PMID 18957941] The A allele of the CLOCK gene SNP rs6832769 was associated with lessened agreeableness (p = 0.00000871) in a group of 3972 Sardinians. The effect remained significant in the replicative American sample, but failed to achieve significance in the Norwegian sample and third sample (though the combined p value remained significant at 0.000865). full paper in pdf

PharmGKBPA164740321
Name
AnnotationGWAS results: Genome-wide association scan for five major dimensions of personality. (Initial Sample Size: 3,972 individuals; Replication Sample Size: 3,903 individuals); (Region: 4q12; Reported Gene(s): CLOCK; Risk Allele: rs6832769-A); (p-value= 0.000002).This variant is associated with Personality dimensions.
GeneCLOCK
Featue
EvidencePubMed ID:18957941; Web Resource:http://www.genome.gov/gwastudies/
Drugs
Diseases
Curation LevelNon-Curated
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