Rs6499640
| Orientation | plus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6499640 |
| PheGenI | rs6499640 |
| nextbio | rs6499640 |
| hapmap | rs6499640 |
| 1000 genomes | rs6499640 |
| hgdp | rs6499640 |
| ensembl | rs6499640 |
| gopubmed | rs6499640 |
| geneview | rs6499640 |
| scholar | rs6499640 |
| rs6499640 | |
| pharmgkb | rs6499640 |
| gwascentral | rs6499640 |
| openSNP | rs6499640 |
| 23andMe | rs6499640 |
| 23andMe all | rs6499640 |
| SNP Nexus | |
| SNPshot | rs6499640 |
| SNPdbe | rs6499640 |
| MSV3d | rs6499640 |
| Gene | FTO |
| Chromosome | 16 |
| Orientation | plus |
| GMAF | 0.4835 |
| Position | 53769677 |
| Reference | GRCh37 37.1/131 |
| Max Magnitude |
| Make rs6499640(A;A) |
| Make rs6499640(A;G) |
| Make rs6499640(G;G) |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
| GWAS snp | |
|---|---|
| PMID | [PMID 19079260] |
| Trait | Body mass index |
| Title | Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity |
| Risk Allele | A |
| P-val | 4E-13 |
| Odds Ratio | 5.25 [3.82-6.68] % SD |
[PMID 20843981] Associations of six single nucleotide polymorphisms in obesity-related genes with BMI and risk of obesity in Chinese children
[PMID 21527513] Influence of physical inactivity on associations between single nucleotide polymorphisms and genetic predisposition to childhood obesity
[PMID 22355368] Longitudinal Replication Studies of GWAS Risk SNPs Influencing Body Mass Index over the Course of Childhood and Adulthood
[PMID 19474294] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.
[PMID 19478790] The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.
[PMID 20712903] Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.
| GET Evidence | |
|---|---|
| rs6499640 | |
| aa_change | |
| aa_change_short | |
| impact | pathogenic |
| qualified_impact | Insufficiently evaluated pathogenic |
| overall_frequency | 0.5625 |
| summary | |
[PMID 23251365] Genetic Variants in the Fat and Obesity Associated (FTO) Gene and Risk of Alzheimer's Disease
