Rs6458307

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is asnp
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dbSNPrs6458307
nextbiors6458307
hapmaprs6458307
1000 genomesrs6458307
hgdprs6458307
ensemblrs6458307
gopubmedrs6458307
scholarrs6458307
googlers6458307
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gwascentralrs6458307
openSNPrs6458307
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SNP Nexus

SNPshotrs6458307
SNPdbers6458307
MSV3drs6458307
Chromosome6
Orientationplus
Position42731115
ReferenceGRCh37 37.1/131
Max Magnitude0
Geno Mag Summary
(C;C) 0 1.4x risk
(C;T) 0.8x risk
(G;G) 0
(T;T) normal
? (C;C) (C;T) (T;T) 28
rs6458307 has been reported in a large study to be associated with bipolar disorder.

The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 0.84 (CI 0.75-0.96), and for homozygotes, 1.39 (CI 1.13-1.69). [PMID 17554300]

GWAS
SNP rs6458307
PubMedID [PMID 17554300]
Condition Bipolar disorder
Gene NR
Risk Allele
pValue 4.00E-006
OR 1.19
95% CI 1.04-1.33


PharmGKBPA162356506
Name
AnnotationGWAS results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,868 cases, 2,938 controls; Replication Sample Size: NR). This variant is associated with Bipolar disorder.
Gene-
Featue
EvidencePubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/
Drugs
DiseasesBipolar Disorder
Curation LevelNon-Curated
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