rs6458307
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | 1.4x risk |
| (C;T) | 0.8x risk | |
| (G;G) | 0 | |
| (T;T) | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 42763377 |
| Gene | GLTSCR1L |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6458307 |
| dbSNP (classic) | rs6458307 |
| ClinGen | rs6458307 |
| ebi | rs6458307 |
| HLI | rs6458307 |
| Exac | rs6458307 |
| Gnomad | rs6458307 |
| Varsome | rs6458307 |
| LitVar | rs6458307 |
| Map | rs6458307 |
| PheGenI | rs6458307 |
| Biobank | rs6458307 |
| 1000 genomes | rs6458307 |
| hgdp | rs6458307 |
| ensembl | rs6458307 |
| geneview | rs6458307 |
| scholar | rs6458307 |
| rs6458307 | |
| pharmgkb | rs6458307 |
| gwascentral | rs6458307 |
| openSNP | rs6458307 |
| 23andMe | rs6458307 |
| SNPshot | rs6458307 |
| SNPdbe | rs6458307 |
| MSV3d | rs6458307 |
| GWAS Ctlg | rs6458307 |
| GMAF | 0.3439 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs6458307 has been reported in a large study to be associated with bipolar disorder.
The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 0.84 (CI 0.75-0.96), and for homozygotes, 1.39 (CI 1.13-1.69). [PMID 17554300
]
| GWAS | |
|---|---|
| SNP | rs6458307 |
| PubMedID | [PMID 17554300]
|
| Condition | Bipolar disorder |
| Gene | NR |
| Risk Allele | |
| pValue | 4.00E-006 |
| OR | 1.19 |
| 95% CI | 1.04-1.33 |
[PMID 19308021] Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort.
