From SNPedia
rs6457617 has been reported in a large study to be associated with rheumatoid arthritis. This SNP is reported to be the most statistically significant of many SNPs similarly located in the MHC region.
The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 2.36 (CI 1.97-2.84), and for homozygotes, 5.21 (CI 4.31-6.30). [PMID 17554300]
| ? | (C;C) (C;T) (T;T) |
|---|
 |
| GWAS snp
|
| PMID
| [PMID 18668548]
|
| Trait
| Rheumatoid arthritis
|
| Title
| Genome-wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility
|
| Risk Allele
|
|
| P-val
| 1.0000000000000001E-9
|
| Odds Ratio
| NR NR
|
[PMID 19714643] TRAF1 polymorphisms associated with rheumatoid arthritis susceptibility in Asians and in Caucasians
