Rs6265(A;G)
From SNPedia
| impaired motor skills learning? |
| Is a | genotype |
| of | rs6265 |
| Gene | BDNF |
| Chromosome | 11 |
| Position | 27,679,916 |
| mentioned | by |
| Magnitude | 2.4 |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 2.5 | introversion; depression resistant; impaired motor skills learning |
| (A;G) | 2.4 | impaired motor skills learning? |
| (G;G) | ? |
On a driving-based motor learning task subjects with this genotype showed greater error during short-term learning and poorer retention over 4 days, relative to subjects without the polymorphism. The presence of this BDNF polymorphism is associated with differences in brain motor system function, altered short-term plasticity, and greater error in short-term motor learning. [PMID 19745020]
Wired discusses the research as does spittoon.
[PMID 17293537] Alzheimer's disease risk for non ApoE4 carriers is affected by the heterozygous form of rs6265
