From SNPedia
| Geno
|
Mag
|
Summary
|
| (C;C)
|
2.1
|
blood type is not O, increased risk for some diseases.
|
| (C;T)
|
|
1.2x risk of pancreatic cancer
|
| (T;T)
|
2
|
blood type O
|
| ? | (C;C) (C;T) (T;T) | 28 |
|---|
 |
each copy rs505922(C) is associated with 1.2x risk of
pancreatic cancer
influences ABO blood group
[PMID 18464913] TNF-alpha (TNF) protein levels
| GWAS snp
|
| PMID
|
[PMID 19278955]
|
| Trait
|
Venous thromboembolism
|
| Title
|
Common susceptibility allele are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach
|
| Risk Allele
|
C
|
| P-val
|
4E-15
|
| Odds Ratio
|
1.81 [1.56-2.11]
|
[PMID 19648918] Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer
| PharmGKB | PA164739926 |
| Name | |
| Annotation | GWAS results: Common susceptibility allele are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach. (Initial Sample Size: 419 cases, 1,228 controls; Replication Sample Size: 1,757 cases, 1,480 controls); (Region: 9q34.2; Reported Gene(s): ABO; Risk Allele: rs505922-C); (p-value= 0.000000000000004).This variant is associated with Venous thromboembolism. |
| Gene | ABO |
| Featue | |
| Evidence | PubMed ID:19278955; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | venous thromboembolism |
| Curation Level | Non-Curated |
[PMID 22147973] Pancreatic cancer risk variant ABO rs505922 in patients with cholangiocarcinoma
| GWAS snp
|
| PMID
|
[PMID 21980494]
|
| Trait
|
|
| Title
|
Genetics of venous thrombosis: insights from a new genome wide association study.
|
| Risk Allele
|
C
|
| P-val
|
1E-34
|
| Odds Ratio
|
1.9200 [NR]
|
| GWAS snp
|
| PMID
|
[PMID 21841780]
|
| Trait
|
|
| Title
|
A genome-wide association study identifies two new risk loci for Graves' disease.
|
| Risk Allele
|
T
|
| P-val
|
0.000008
|
| Odds Ratio
|
1.1300 [1.07-1.20]
|
[PMID 22387998] A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population
