Rs4146894(A;A)

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9.1x risk for AMD, but replication is lacking
Is agenotype
ofrs4146894
GenePLEKHA1
Chromosome10
Position124,155,381
mentionedby
Magnitude2.1
Geno Mag Summary
(A;A) 2.1 9.1x risk for AMD, but replication is lacking
(A;G) 2.6x risk for AMD
(G;G) 0 average

A study in 2007 identified this and two other variants (rs10490924 and rs11200638) as indicating a 9x risk of age related macular degeneration. The other two snps are now well replicated, but replications of the snp you have are still lacking.

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