rs276174846

plus

Geno	Mag	Summary
(ATTAGC;ATTAGC)	0	common in clinvar
(G;ATTAGC)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs276174846(ATTAGC;G)

Make rs276174846(G;G)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32339086

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs276174846
dbSNP (classic)	rs276174846
ClinGen	rs276174846
ebi	rs276174846
HLI	rs276174846
Exac	rs276174846
Gnomad	rs276174846
Varsome	rs276174846
LitVar	rs276174846
Map	rs276174846
PheGenI	rs276174846
Biobank	rs276174846
1000 genomes	rs276174846
hgdp	rs276174846
ensembl	rs276174846
geneview	rs276174846
scholar	rs276174846
google	rs276174846
pharmgkb	rs276174846
gwascentral	rs276174846
openSNP	rs276174846
23andMe	rs276174846
SNPshot	rs276174846
SNPdbe	rs276174846
MSV3d	rs276174846
GWAS Ctlg	rs276174846

Max Magnitude

6

rs276174846, also known as 4959del6insG, c.4731_4736delATTAGCinsG and p.Glu1577_Ala1579?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs276174846(G;G)
Alt	rs276174846(G;G)
Reference	Rs276174846(ATTAGC;ATTAGC)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32913223_32913228delATTAGCinsG
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044478.2, RCV000113338.1, RCV000223243.1,