rs2266780

plus

Geno	Mag	Summary
(A;A)	0	common in clinvar

Make rs2266780(A;G)

Make rs2266780(G;G)

Reference

GRCh38 38.1/141

Chromosome

1

Position

171114102

Gene

FMO3

is a	snp
is	mentioned by
dbSNP	rs2266780
dbSNP (classic)	rs2266780
ClinGen	rs2266780
ebi	rs2266780
HLI	rs2266780
Exac	rs2266780
Gnomad	rs2266780
Varsome	rs2266780
LitVar	rs2266780
Map	rs2266780
PheGenI	rs2266780
Biobank	rs2266780
1000 genomes	rs2266780
hgdp	rs2266780
ensembl	rs2266780
geneview	rs2266780
scholar	rs2266780
google	rs2266780
pharmgkb	rs2266780
gwascentral	rs2266780
openSNP	rs2266780
23andMe	rs2266780
SNPshot	rs2266780
SNPdbe	rs2266780
MSV3d	rs2266780
GWAS Ctlg	rs2266780

GMAF

0.1299

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

OMIM	136132
Desc
Variant	0015
Related	also

ClinVar
Risk	rs2266780(G;G)
Alt	rs2266780(G;G)
Reference	Rs2266780(A;A)
Significance	Pathogenic
Disease	Trimethylaminuria not specified
Variation	info
Gene	FMO3
CLNDBN	Trimethylaminuria, mild Trimethylaminuria not specified
Reversed	0
HGVS	NC_000001.10:g.171083242A>G
CLNSRC	OMIM Allelic Variant UniProtKB (protein)
CLNACC	RCV000017711.6, RCV000201276.1, RCV000254132.1, RCV000290538.1,

[PMID 15858076] Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants.

[PMID 18565990 ] Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence.

[PMID 9536088] Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication.

[PMID 10485731] Mild trimethylaminuria caused by common variants in FMO3 gene.

[PMID 24165757] The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantation

[PMID 24173915] Effects of single nucleotide polymorphisms of FMO3 and FMO6 genes on pharmacokinetic characteristics of sulindac sulfide in premature labor