Rs2230201
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs2230201 |
| hapmap | rs2230201 |
| hgdp | rs2230201 |
| ensembl | rs2230201 |
| gopubmed | rs2230201 |
| scholar | rs2230201 |
| rs2230201 | |
| pharmgkb | rs2230201 |
| hgvbaseg2p | rs2230201 |
| medrefsnp | rs2230201 |
| 23andMe | rs2230201 |
| SNP Nexus |
| Gene | C3 |
| Chromosome | 19 |
| Orientation | minus |
| Position | 6664290 |
| Genotype | Effect |
|---|---|
| rs2230201(G;G) | >1.4x risk of lupus |
| rs2230201(A;G) | 1.4x risk of lupus |
| rs2230201(A;A) | normal risk |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs2230201(A;A) | normal risk | |
| Rs2230201(A;G) | 1.4x risk of lupus | |
| Rs2230201(G;G) | >1.4x risk of lupus |
In ~500 Japanese SLE patients, the (G) allele of rs2230201, a SNP in the C3 gene, is associated with higher risk for systemic lupus erythematosus (SLE). The odds ratio is 1.19 (CI: 1.01-1.41, p=0.038).[PMID 18174230]
| ? | (G;G) |
|---|---|
|
| |
| Neighbor | rs1047286 |
| Distance | 29 |
