Rs2167270
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs2167270 |
| nextbio | rs2167270 |
| hapmap | rs2167270 |
| 1000 genomes | rs2167270 |
| hgdp | rs2167270 |
| ensembl | rs2167270 |
| gopubmed | rs2167270 |
| scholar | rs2167270 |
| rs2167270 | |
| pharmgkb | rs2167270 |
| gwascentral | rs2167270 |
| openSNP | rs2167270 |
| 23andMe | rs2167270 |
| 23andMe all | rs2167270 |
| SNP Nexus | |
| SNPshot | rs2167270 |
| SNPdbe | rs2167270 |
| MSV3d | rs2167270 |
| Gene | LEP |
| Chromosome | 7 |
| Orientation | plus |
| Position | 127881349 |
| Reference | GRCh37 37.1/131 |
| Max Magnitude | 0 |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0.79x reduced risk for colon cancer | |
| (A;G) | 0 | normal |
| (G;G) | 0 | normal |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
In a study of ~1,500 colon cancer patients, the rs2167270(A;A) genotype was underrepresented, leading to an odds ratio of 0.79 (CI: 0.64-0.98).[PMID 18059035]
[PMID 20140086] Genetic Variation at Selected SNPs in the Leptin Gene and Association of Alleles with Markers of Kidney Disease in a Xhosa Population of South Africa
[PMID 21512510] The Effect of Ponderal Index at Birth on the Relationships Between Common LEP and LEPR Polymorphisms and Adiposity in Adolescents
