Rs1805762

From SNPedia

Jump to: navigation, search
is asnp
is mentioned by
dbSNPrs1805762
hapmaprs1805762
hgdprs1805762
ensemblrs1805762
gopubmedrs1805762
scholarrs1805762
googlers1805762
pharmgkbrs1805762
hgvbaseg2prs1805762
medrefsnprs1805762
23andMers1805762
SNP Nexus

GeneM6PR
Chromosome12
Orientationminus
Position8989168
GenotypeEffect
rs1805762(C;C)>1.23x risk for hypertension
rs1805762(C;G)1.23x risk for hypertension
rs1805762(G;G)average


Genotypes Magnitude Summary
Rs1805762(C;C) >1.23x risk for hypertension
Rs1805762(C;G) 1.23x risk for hypertension
Rs1805762(G;G) average
rs1805762, a SNP in the M6PR gene, was associated with risk for hypertension in a study involving 1,500+ Japanese patients. The odds ratio associated with the risk allele, in dbSNP orientation, rs1805762(G), which is also the most common allele, is 1.23 (CI: 1.10 - 1.37, p = 0.0003). [PMID 18003638]

A SNP in close linkage, rs1805740, has also been reported in association with hypertension risk in the large 2007 study reported by the Wellcome Trust Consortium. [PMID 17554300]

? (C;C) (C;G) (G;G)