Rs1804197

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is asnp
is mentioned by
dbSNPrs1804197
hapmaprs1804197
hgdprs1804197
ensemblrs1804197
gopubmedrs1804197
scholarrs1804197
googlers1804197
pharmgkbrs1804197
hgvbaseg2prs1804197
medrefsnprs1804197
23andMers1804197
SNP Nexus

GeneAPC
Chromosome5
Orientationplus
Position112207807
GenotypeEffect
rs1804197(A;A)*?
rs1804197(A;C)*?
rs1804197(C;C)*?


rs1804197, a SNP in the adenomatous polyposis of the colon APC gene, is associated with autism [PMID 17221838].

Although many SNPs have been found in this gene in association with (successful) hunts for mutations predisposing individuals to colon cancers, this previously unidentified SNP is located in the 3' untranslated portion of the gene. Also in conjunction with a common four-SNP haplotype (TGAG for rs2229992, rs42427, rs459552, and rs465899), this SNP is reported to be associated with Asperger's sydrome in the Swedish population studied. [PMID 17221838]