Rs1801260
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs1801260 |
| hapmap | rs1801260 |
| hgdp | rs1801260 |
| ensembl | rs1801260 |
| gopubmed | rs1801260 |
| scholar | rs1801260 |
| rs1801260 | |
| pharmgkb | rs1801260 |
| hgvbaseg2p | rs1801260 |
| medrefsnp | rs1801260 |
| 23andMe | rs1801260 |
| SNP Nexus |
| Gene | CLOCK |
| Chromosome | 4 |
| Orientation | minus |
| Position | 55996126 |
| Genotype | Effect |
|---|---|
| rs1801260(C;C)* | ? |
| rs1801260(C;T)* | ? |
| rs1801260(T;T)* | ? |
rs1801260, a SNP in the CLOCK gene known as 3111 T/C, has been reported to influence sleep and activity patterns in patients affected by bipolar depression. [PMID 17221848]
From this article's abstract:
"Compared to T/T homozygotes, carriers of the C allele had a similar degree of severity of depression, but showed higher activity levels in the evening, a delayed sleep onset (mean 79 min later), and a reduced amount of sleep during the night (mean 75 min less)."
| ? | (C;C) (C;T) (T;T) |
|---|---|
|
| |
