Rs1800787

From SNPedia

Jump to: navigation, search
is asnp
is mentioned by
dbSNPrs1800787
hapmaprs1800787
hgdprs1800787
ensemblrs1800787
gopubmedrs1800787
scholarrs1800787
googlers1800787
pharmgkbrs1800787
hgvbaseg2prs1800787
medrefsnprs1800787
23andMers1800787
SNP Nexus

GeneFGB
Chromosome4
Orientationplus
Position155703464
GenotypeEffect
rs1800787(C;C)*?
rs1800787(C;T)*?
rs1800787(T;T)


Genotypes Magnitude Summary
Rs1800787(T;T)

rs1800787(T;T) homozygotes are at 6 fold higher risk compared to (C;C) homozygotes or (C;T) heterozygotes for carotid atherosclerosis [PMID 9514419]. This polymorphism is known as the "C148-T" variant, and is located in at the "-148" position of the FGB gene, also known as beta fibrinogen.

[PMID 18726528] A meta-analysis of 7 studies did not find a significant association between the -148C/T FGB SNP and susceptibility to coronary artery disease in Chinese populations.

Note: due to inconsistencies between databases and the literature, the association of this rs# with this polymorphism name as published is highly likely but not guaranteed.