rs17632542

plus

Geno	Mag	Summary
(T;T)	0	common in complete genomics

Make rs17632542(C;C)

Make rs17632542(C;T)

Reference

GRCh38 38.1/141

Chromosome

19

Position

50858501

Gene

KLK3

is a	snp
is	mentioned by
dbSNP	rs17632542
dbSNP (classic)	rs17632542
ClinGen	rs17632542
ebi	rs17632542
HLI	rs17632542
Exac	rs17632542
Gnomad	rs17632542
Varsome	rs17632542
LitVar	rs17632542
Map	rs17632542
PheGenI	rs17632542
Biobank	rs17632542
1000 genomes	rs17632542
hgdp	rs17632542
ensembl	rs17632542
geneview	rs17632542
scholar	rs17632542
google	rs17632542
pharmgkb	rs17632542
gwascentral	rs17632542
openSNP	rs17632542
23andMe	rs17632542
SNPshot	rs17632542
SNPdbe	rs17632542
MSV3d	rs17632542
GWAS Ctlg	rs17632542

GMAF

0.03168

Max Magnitude

0

?

(C;C) (C;T) (T;T)

28

GWAS snp
PMID	[PMID 21160077 ]
Trait
Title	Genetic Correction of PSA Values Using Sequence Variants Associated with PSA Levels
Risk Allele	T
P-val	3E-46
Odds Ratio	39.1000 [NR] % increase

[PMID 21465221 ] Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript

[PMID 21318478 ] Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels.

[PMID 23359319 ] Genome-wide Association Study Identifies Loci at ATF7IP and KLK2 Associated with Percentage of Circulating Free PSA

[PMID 23937305 ] Validation of association of genetic variants at 10q with prostate-specific antigen (PSA) levels in men at high risk for prostate cancer

[PMID 24345439 ] Prostate cancer risk alleles are associated with prostate cancer tumor volume and prostate size

[PMID 23246478 ] Personalized prostate specific antigen testing using genetic variants may reduce unnecessary prostate biopsies.

GWAS snp
PMID	[PMID 24753544 ]
Trait	Prostate cancer
Title	Genetic variation in prostate-specific antigen-detected prostate cancer and the effect of control selection on genetic association studies.
Risk Allele	T
P-val	2E-28
Odds Ratio	.73 [0.60-0.86] unit increase

GWAS snp
PMID	[PMID 24740154 ]
Trait	Prostate cancer (early onset)
Title	Genome-wide association scan for variants associated with early-onset prostate cancer.
Risk Allele	T
P-val	1E-7
Odds Ratio	1.85 [1.61-2.09]