From SNPedia
rs17445836 is a SNP in the region of the IRF8 gene.
A large study (~5,000 patients) found an increased risk for multiple sclerosis associated with rs17445836; the odds ratio for the minor allele was reported as 0.80 (CI: 0.72-0.89, p=3.73x10(-9)).10.1038/ng.401
| GWAS snp
|
| PMID
| [PMID 19525953]
|
| Trait
| Multiple sclerosis
|
| Title
| Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
|
| Risk Allele
| G
|
| P-val
| 4E-9
|
| Odds Ratio
| 1.25 [1.12-1.39]
|
| ? | (A;A) (A;G) (G;G) |
|---|
 |
