| ? | (A;A) (A;C) (C;C) | 28 |
|---|
 |
| GWAS
|
| SNP
|
rs1701704
|
| PubMedID
|
[PMID 18198356]
|
| Condition
|
Type 1 diabetes
|
| Gene
|
RAB5B, SUOX, IKZF4, ERBB3, CDK2
|
| Risk Allele
|
C
|
| pValue
|
9.00E-010
|
| OR
|
1.25
|
| 95% CI
|
1.12-1.40
|
| GWAS snp
|
| PMID
|
[PMID 20596022]
|
| Trait
|
Alopecia areata
|
| Title
|
Genome-wide association study in alopecia areata implicates both innate and adaptive immunity
|
| Risk Allele
|
C
|
| P-val
|
3E-8
|
| Odds Ratio
|
1.34 [1.21-1.48]
|
| GWAS snp
|
| PMID
|
[PMID 21804548]
|
| Trait
|
|
| Title
|
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.
|
| Risk Allele
|
G
|
| P-val
|
2E-13
|
| Odds Ratio
|
1.1900 [1.14-1.25]
|
| GWAS snp
|
| PMID
|
[PMID 21829393]
|
| Trait
|
|
| Title
|
Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.
|
| Risk Allele
|
T
|
| P-val
|
5E-18
|
| Odds Ratio
|
1.2500 [NR]
|
[PMID 18840781] Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.
[PMID 20668683] Genetically dependent ERBB3 expression modulates antigen presenting cell function and type 1 diabetes risk.
| GET Evidence
|
| rs1701704
|
| aa_change
|
|
| aa_change_short
|
|
| impact
|
pathogenic
|
| qualified_impact
|
Insufficiently evaluated pathogenic
|
| overall_frequency
|
0.195312
|
| summary
|
|
[PMID 23721563] Associations of polymorphisms in non-HLA loci with autoantibodies at the diagnosis of type 1 diabetes: INS and IKZF4 associate with insulin autoantibodies
