From SNPedia
| ? | (A;A) (A;G) (G;G) | 28 |
|---|
 |
[
PMID 17529974]
rs13387042(A;A) on has an estimated 1.44-fold greater risk than noncarriers,
This initial association was later tested among patients in the Breast Cancer Association Consortium, including 31,510 women with invasive breast cancer, 1101 women with ductal carcinoma in situ, and 35,969 controls. The association was confirmed for Caucasian women of European origin, with a per allele odds ratio of 1.12 (CI: 1.09-1.15). This association held regardless of ER or PR status.[PMID 19567422]
| GWAS
|
| SNP
| rs13387042
|
| PubMedID
| [PMID 17529974]
|
| Condition
| Breast cancer
|
| Gene
| Intergenic
|
| Risk Allele
| A
|
| pValue
| 1.00E-013
|
| OR
| 1.2
|
| 95% CI
| 1.14-1.26
|
| GWAS snp
|
| PMID
| [PMID 19330030]
|
| Trait
| Breast cancer
|
| Title
| A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)
|
| Risk Allele
| A
|
| P-val
| 2E-8
|
| Odds Ratio
|
|
[PMID 19656774] Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers
| PharmGKB | PA161925625 |
| Name | |
| Annotation | This variant is significantly associated with risk for breast cancer. Carriers of the A allele had an estimated 1.44-fold greater risk than noncarriers. |
| Gene | - |
| Featue | |
| Evidence | PubMed ID:17529974 |
| Drugs | |
| Diseases | Breast Neoplasms |
| Curation Level | Curated |
[PMID 19789366] Evaluation of 11 breast cancer susceptibility loci in African-American women
| GWAS snp
|
| PMID
| [PMID 20453838]
|
| Trait
| Breast cancer
|
| Title
| Genome-wide association study identifies five new breast cancer susceptibility loci
|
| Risk Allele
| A
|
| P-val
| 2E-10
|
| Odds Ratio
| 1.21 [1.14-1.29]
|
[PMID 20664043] Incidence of breast cancer and its subtypes in relation to individual and multiple low-penetrance genetic susceptibility loci
