From SNPedia
[
PMID 18437204]
breast cancer
- rs13281615 in 8q24 was stronger for ER-positive, PR-positive, and low grade tumors (P = 0.001, 0.011 and 10(-4), respectively) and improvement in survival after diagnosis (per-allele HR = 0.90 (0.83-0.97).
[PMID 19005751] rs13281615 confirmed in 988 sporadic breast cancer cases and 1,016 controls from the West of Ireland to be associated with increased risk (odds ratio 1.17, p(allelic) = 1.8 x 10e-2) for breast cancer
| ? | (A;A) (A;G) (G;G) |
|---|
 |
| GWAS
|
| SNP
| rs13281615
|
| PubMedID
| [PMID 17529967]
|
| Condition
| Breast cancer
|
| Gene
| Intergenic
|
| Risk Allele
| T
|
| pValue
| 5.00E-012
|
| OR
| 1.08
|
| 95% CI
| 1.05-1.11
|
[PMID 19656774] Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers
| PharmGKB | PA162356621 |
| Name | |
| Annotation | GWAS Results: Genome-wide association study identifies novel breast cancer susceptibility loci (Initial Sample Size: 390 cases, 364 controls; Replication Sample Size: 26,646 cases, 24,889 controls; Risk Allele: rs13281615-T). |
| Gene | - |
| Featue | |
| Evidence | PubMed ID:17529967; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Breast Neoplasms |
| Curation Level | Non-Curated |
