rs12951053
| Orientation | plus |
| Stabilized | plus |
| Make rs12951053(A;A) |
| Make rs12951053(A;C) |
| Make rs12951053(C;C) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 17 |
| Position | 7674089 |
| Gene | TP53 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs12951053 |
| dbSNP (classic) | rs12951053 |
| ClinGen | rs12951053 |
| ebi | rs12951053 |
| HLI | rs12951053 |
| Exac | rs12951053 |
| Gnomad | rs12951053 |
| Varsome | rs12951053 |
| LitVar | rs12951053 |
| Map | rs12951053 |
| PheGenI | rs12951053 |
| Biobank | rs12951053 |
| 1000 genomes | rs12951053 |
| hgdp | rs12951053 |
| ensembl | rs12951053 |
| geneview | rs12951053 |
| scholar | rs12951053 |
| rs12951053 | |
| pharmgkb | rs12951053 |
| gwascentral | rs12951053 |
| openSNP | rs12951053 |
| 23andMe | rs12951053 |
| SNPshot | rs12951053 |
| SNPdbe | rs12951053 |
| MSV3d | rs12951053 |
| GWAS Ctlg | rs12951053 |
| GMAF | 0.1635 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
[PMID 17683073] rs17887200 and rs12951053 associated with ER negative breast cancer tumors (1.48 (1.11-1.93) p-trend = 0.01 and 1.29 (1.06-1.58) p-trend = 0.009, respectively)
A study population including a total of 5,206 invasive ovarian cancer cases (2,829 of which were serous) and 8,790 controls found an association between rs12951053 and serous invasive cancer (median per allele odds ratio 1.19, CI: 1.01-1.38).[PMID 19276375
]
[PMID 19423538] Common Genetic Variation in TP53 and Risk of Human Papillomavirus Persistence and Progression to CIN3/Cancer Revisited
[PMID 20386703] Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer
[PMID 22291954] Association between Variations in Cell Cycle Genes and Idiopathic Pulmonary Fibrosis
[PMID 17301252] Common genetic variation in TP53 is associated with lung cancer risk and prognosis in African Americans and somatic mutations in lung tumors.
[PMID 17449902] Genetic variation in TP53 and risk of breast cancer in a population-based case control study.
[PMID 18640487] Association of donor inflammation- and apoptosis-related genotypes and delayed allograft function after kidney transplantation.
[PMID 18978339] Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity.
[PMID 21536413] POMC and TP53 genetic variability and risk of basal cell carcinoma of skin: Interaction between host and genetic factors.
[PMID 23124483] Correlation of telomere length shortening with TP53 somatic mutations, polymorphisms and allelic loss in breast tumors and esophageal cancer.
[PMID 23435014] Differential mutation profiles and similar intronic TP53 polymorphisms in asbestos-related lung cancer and pleural mesothelioma.
