Rs12487066
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs12487066 |
| hapmap | rs12487066 |
| hgdp | rs12487066 |
| ensembl | rs12487066 |
| gopubmed | rs12487066 |
| scholar | rs12487066 |
| rs12487066 | |
| pharmgkb | rs12487066 |
| hgvbaseg2p | rs12487066 |
| medrefsnp | rs12487066 |
| 23andMe | rs12487066 |
| SNP Nexus |
| Gene | CBLB |
| Chromosome | 3 |
| Orientation | plus |
| Position | 107394819 |
| Genotype | Effect |
|---|---|
| rs12487066(C;C) | >1.09x increased risk for multiple sclerosis |
| rs12487066(C;T) | 1.09x increased risk for multiple sclerosis |
| rs12487066(T;T) | common |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs12487066(C;C) | 00 | >1.09x increased risk for multiple sclerosis |
| Rs12487066(C;T) | 1.09x increased risk for multiple sclerosis | |
| Rs12487066(T;T) | common |
The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with this allele is 1.09 (CI 1.03-1.16). [PMID 17660530]
| ? | (C;C) (C;T) (T;T) |
|---|---|
|
| |
| PharmGKB | PA162356172 |
| Name | |
| Annotation | In a replicated GWAS of U.K. and U.S. case/parent trios, this variant was shown to be associated with multiple sclerosis risk. |
| Gene | - |
| Featue | |
| Evidence | PubMed ID:17660530 |
| Drugs | |
| Diseases | Multiple Sclerosis |
| Curation Level | Curated |
