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Rs12487066

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Orientationplus
is asnp
is mentioned by
dbSNPrs12487066
PheGenIrs12487066
nextbiors12487066
hapmaprs12487066
1000 genomesrs12487066
hgdprs12487066
ensemblrs12487066
gopubmedrs12487066
geneviewrs12487066
scholarrs12487066
googlers12487066
pharmgkbrs12487066
gwascentralrs12487066
openSNPrs12487066
23andMers12487066
23andMe allrs12487066
SNP Nexus

SNPshotrs12487066
SNPdbers12487066
MSV3drs12487066
GeneCBLB
Chromosome3
Orientationplus
GMAF0.2612
Position106193283
ReferenceGRCh38 38.1/141
Max Magnitude0
Geno Mag Summary
(C;C) 0 >1.09x increased risk for multiple sclerosis
(C;T) 1.09x increased risk for multiple sclerosis
(T;T) common
? (C;C) (C;T) (T;T) 28
rs12487066 has been reported in a large study to be associated with multiple sclerosis.

The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with this allele is 1.09 (CI 1.03-1.16). [PMID 17660530]



[PMID 20007504OA-icon.png] Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci.


GET Evidence
rs12487066
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.289062
summary



[PMID 22492128] Association of SNPs rs6498169 and rs10984447 with multiple sclerosis in Saudi patients: a model of the usefulness of familial aggregates in identifying genetic linkage in a multifactorial disease.