| Geno
|
Mag
|
Summary
|
| (C;C)
|
0
|
>1.09x increased risk for multiple sclerosis
|
| (C;T)
|
|
1.09x increased risk for multiple sclerosis
|
| (T;T)
|
|
common
|
| ? | (C;C) (C;T) (T;T) | 28 |
|---|
 |
has been reported in a large study to be associated with
multiple sclerosis.
The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with this allele is 1.09 (CI 1.03-1.16). [PMID 17660530]
[PMID 20007504] Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci.
| GET Evidence
|
| rs12487066
|
| aa_change
|
|
| aa_change_short
|
|
| impact
|
pharmacogenetic
|
| qualified_impact
|
Insufficiently evaluated pharmacogenetic
|
| overall_frequency
|
0.289062
|
| summary
|
|
