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rs12487066 has been reported in a large study to be associated with multiple sclerosis.
The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with this allele is 1.09 (CI 1.03-1.16). [PMID 17660530]
[PMID 20007504] Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci.
|qualified_impact||Insufficiently evaluated pharmacogenetic|
[PMID 22492128] Association of SNPs rs6498169 and rs10984447 with multiple sclerosis in Saudi patients: a model of the usefulness of familial aggregates in identifying genetic linkage in a multifactorial disease.