Rs1205

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dbSNPrs1205
hapmaprs1205
hgdprs1205
ensemblrs1205
gopubmedrs1205
scholarrs1205
googlers1205
pharmgkbrs1205
hgvbaseg2prs1205
medrefsnprs1205
23andMers1205
SNP Nexus

GeneCRP
Chromosome1
Orientationplus
Position157948856
GenotypeEffect
rs1205(C;C)*?
rs1205(C;T)*?
rs1205(T;T)*?


Although somewhat lacking in statistical power, several reports have linked rs1205, a synonymous mutation known as CRP4 in the C-reactive protein CRP to the autoimmune disorder SLE, systemic lupus erythematosus. The risk allele in dbSNP orientation is (T). [PMID 14645206, PMID 15897982]

[PMID 19139754] C-reactive protein (CRP) levels obesity rs1205(G) allele had significantly higher CRP levels than noncarriers in a dose-dependent manner suggesting a possible association with fat localization

spittoon each rs1205(T) lowered CRP by 20% but no association with heart disease.

Related to C-REACTIVE PROTEIN, PENTRAXIN-RELATED; CRP according to omim 123260. See also


? (C;C) (C;T) (T;T)


[PMID 19040303] C-reactive protein gene polymorphisms in biopsy-proven giant cell arteritis from Northwestern Spain


[PMID 19433520] Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: The Health in Men Study

Related to STROKE, ISCHEMIC according to omim 601367. See also


Related to SYSTEMIC LUPUS ERYTHEMATOSUS; SLE according to omim 152700. See also


[PMID 19101671] Association between C-reactive protein gene haplotypes and C-reactive protein levels in Taiwanese: interaction with obesity

[PMID 19692124] Complement Factor H Y402H and C-Reactive Protein Polymorphism and Photodynamic Therapy Response in Age-Related Macular Degeneration