| Geno
|
Mag
|
Summary
|
| (A;A)
|
0
|
common in complete genomics
|
| ? | (A;A) (A;G) (G;G) | 28 |
|---|
 |
| GWAS snp
|
| PMID
|
[PMID 18587394]
|
| Trait
|
Crohn's disease
|
| Title
|
Genome-wide assocation defines more than 30 distinct susceptibility loci for Crohn's disease
|
| Risk Allele
|
G
|
| P-val
|
2.9999999999999999E-16
|
| Odds Ratio
|
1.33 [NR]
|
| OMIM | 612278 |
| Desc | INFLAMMATORY BOWEL DISEASE 19; IBD19 |
| Variant | |
| Related | also |
[PMID 19557189] Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.
[PMID 20106866] Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.
[PMID 22065112] The JAK2 variant rs10758669 in Crohn's disease: altering the intestinal barrier as one mechanism of action.
| GET Evidence
|
| rs11747270
|
| aa_change
|
|
| aa_change_short
|
|
| impact
|
pathogenic
|
| qualified_impact
|
Insufficiently evaluated pathogenic
|
| overall_frequency
|
0.285714
|
| summary
|
|
