Rs11196205

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Orientationplus
Make rs11196205(C;C)
Make rs11196205(C;G)
Make rs11196205(G;G)
ReferenceGRCh38 38.1/141
Chromosome10
Position113047288
GeneTCF7L2
is asnp
is mentioned by
dbSNPrs11196205
PheGenIrs11196205
nextbiors11196205
hapmaprs11196205
1000 genomesrs11196205
hgdprs11196205
ensemblrs11196205
gopubmedrs11196205
geneviewrs11196205
scholarrs11196205
googlers11196205
pharmgkbrs11196205
gwascentralrs11196205
openSNPrs11196205
23andMers11196205
23andMe allrs11196205
SNP Nexus

SNPshotrs11196205
SNPdbers11196205
MSV3drs11196205
GMAF0.4197
Max Magnitude
? (C;C) (C;G) (G;G) 28

[PMID 17340123] rs12255372, rs7903146, rs7901695 and rs11196205 associated with type-2 diabetes

OMIM602228
DescTRANSCRIPTION FACTOR 7-LIKE 2; TCF7L2
Variant
Relatedalso
[PMID 20028944OA-icon.png] Gene variants of TCF7L2 influence weight loss and body composition during lifestyle intervention in a risk population for type 2 diabetes
OMIM602228
Desc
Variant0003
Relatedalso


[PMID 22441719] Stronger Association of Common Variants in TCF7L2 Gene with Nonobese Type 2 Diabetes in the Latvian Population


[PMID 22511877OA-icon.png] Type 2 Diabetes Risk Alleles Demonstrate Extreme Directional Differentiation among Human Populations, Compared to Other Diseases


[PMID 16936218] Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance.


[PMID 17245589] A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population.


[PMID 17311858] TCF7L2 gene polymorphisms confer an increased risk for early impairment of glucose metabolism and increased height in obese children.


[PMID 17601994] Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy.


[PMID 17609304] Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese.


[PMID 17661009OA-icon.png] Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.


[PMID 17934151] A variant of the transcription factor 7-like 2 (TCF7L2) gene and the risk of posttransplantation diabetes mellitus in renal allograft recipients.


[PMID 17971425OA-icon.png] Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans.


[PMID 18097733] Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects.


[PMID 18268068OA-icon.png] Variation in TCF7L2 and increased risk of colon cancer: the Atherosclerosis Risk in Communities (ARIC) Study.


[PMID 18291022OA-icon.png] Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population.


[PMID 18397358] TCF7L2 polymorphisms are associated with type 2 diabetes in Khatri Sikhs from North India: genetic variation affects lipid levels.


[PMID 18437354OA-icon.png] TCF7L2 single nucleotide polymorphisms, cardiovascular disease and all-cause mortality: the Atherosclerosis Risk in Communities (ARIC) study.


[PMID 18598350OA-icon.png] Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk.


[PMID 18650481OA-icon.png] TCF7L2 variants associate with CKD progression and renal function in population-based cohorts.


[PMID 18655717OA-icon.png] Weak or no association of TCF7L2 variants with Type 2 diabetes risk in an Arab population.


[PMID 19228405OA-icon.png] Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis.


[PMID 19482368] Meta-analysis of the association between SNPs in TCF7L2 and type 2 diabetes in East Asian population.


[PMID 19924244OA-icon.png] TCF7L2 polymorphism rs7903146 is associated with coronary artery disease severity and mortality.


[PMID 21133856OA-icon.png] Genome-wide association scan allowing for epistasis in type 2 diabetes.


[PMID 21159844] Variants and haplotypes of TCF7L2 are associated with beta-cell function in patients with newly diagnosed type 2 diabetes: the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 1.


[PMID 21423583OA-icon.png] Single nucleotide polymorphisms of TCF7L2 are linked to diabetic coronary atherosclerosis.


[PMID 23041303] Association between donor and recipient TCF7L2 gene polymorphisms and the risk of new-onset diabetes mellitus after liver transplantation in a Han Chinese population


[PMID 23577093OA-icon.png] Association of TCF7L2 Gene Polymorphisms with T2DM in the Population of Hyderabad, India


[PMID 23188737] TCF7L2 gene polymorphisms and type 2 diabetes risk: a comprehensive and updated meta-analysis involving 121,174 subjects


[PMID 23107111] Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects.


[PMID 25274455] The gene polymorphisms of UCP1 but not PPAR γ and TCF7L2 are associated with diabetic retinopathy in Chinese type 2 diabetes mellitus cases