Rs10871454
From SNPedia
| Orientation | plus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10871454 |
| PheGenI | rs10871454 |
| nextbio | rs10871454 |
| hapmap | rs10871454 |
| 1000 genomes | rs10871454 |
| hgdp | rs10871454 |
| ensembl | rs10871454 |
| gopubmed | rs10871454 |
| geneview | rs10871454 |
| scholar | rs10871454 |
| rs10871454 | |
| pharmgkb | rs10871454 |
| gwascentral | rs10871454 |
| openSNP | rs10871454 |
| 23andMe | rs10871454 |
| 23andMe all | rs10871454 |
| SNP Nexus | |
| SNPshot | rs10871454 |
| SNPdbe | rs10871454 |
| MSV3d | rs10871454 |
| Gene | STX4 |
| Chromosome | 16 |
| Orientation | plus |
| GMAF | 0.4661 |
| Position | 31048079 |
| Reference | GRCh37 37.1/131 |
| Max Magnitude |
| Make rs10871454(C;C) |
| Make rs10871454(C;T) |
| Make rs10871454(T;T) |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
| GWAS snp | |
|---|---|
| PMID | [PMID 18535201] |
| Trait | Warfarin maintenance dose |
| Title | A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose |
| Risk Allele | |
| P-val | 5.0000000000000003E-34 |
| Odds Ratio | NR NR |
[PMID 21063236] Dependency of phenprocoumon dosage on polymorphisms in the VKORC1, CYP2C9, and CYP4F2 genes
[PMID 22321278] [Impact of CYP2C9 and VKORC1 polymorphism on warfarin response during initiation of therapy]
[PMID 19578179] A genome-wide association study of acenocoumarol maintenance dosage.
[PMID 22178823] [Distribution of variant alleles association with warfarin pharmacokinetics and pharmacodynamics in the Han population in China].
| GET Evidence | |
|---|---|
| rs10871454 | |
| aa_change | |
| aa_change_short | |
| impact | pathogenic |
| qualified_impact | Insufficiently evaluated pathogenic |
| overall_frequency | 0.34375 |
| summary | |
