rs107251
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in complete genomics |
| Make rs107251(C;T) |
| Make rs107251(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 19 |
| Position | 4176088 |
| Gene | SIRT6 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs107251 |
| dbSNP (classic) | rs107251 |
| ClinGen | rs107251 |
| ebi | rs107251 |
| HLI | rs107251 |
| Exac | rs107251 |
| Gnomad | rs107251 |
| Varsome | rs107251 |
| LitVar | rs107251 |
| Map | rs107251 |
| PheGenI | rs107251 |
| Biobank | rs107251 |
| 1000 genomes | rs107251 |
| hgdp | rs107251 |
| ensembl | rs107251 |
| geneview | rs107251 |
| scholar | rs107251 |
| rs107251 | |
| pharmgkb | rs107251 |
| gwascentral | rs107251 |
| openSNP | rs107251 |
| 23andMe | rs107251 |
| SNPshot | rs107251 |
| SNPdbe | rs107251 |
| MSV3d | rs107251 |
| GWAS Ctlg | rs107251 |
| GMAF | 0.1786 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
One study found that individuals with either the CC or CT genotype at rs107251 within SIRT6 displayed >5-year mean survival advantages compared to the TT genotype (5.5 and 5.9 years, respectively; q-value = 0.012).
[PMID 25541994
]
[PMID 22087257] Association of the Sirtuin and Mitochondrial Uncoupling Protein Genes with Carotid Plaque
[PMID 25541994] SIRT6 Minor Allele Genotype Is Associated with >5-Year Decrease in Lifespan in an Aged Cohort.
[PMID 33380799] Correlations Between SIRT Genetic Polymorphisms and Postpartum Depressive Symptoms in Chinese Parturients Who Had Undergone Cesarean Section.
