rs104895094, also known as K695R, is a SNP in the MEFV gene. The risk allele is given as (C) by 23andMe, however in dbSNP orientation, the risk allele is (G).
The symptoms of familial Mediterranean fever are caused by the person's own inflammatory response; it is not an infectious disease. The condition is more common among Turks, Sephardic Jews, and people of Arab and Armenian ancestry.
|Disease||Familial Mediterranean fever Familial mediterranean fever|
|CLNDBN||Familial Mediterranean fever Familial mediterranean fever, autosomal dominant|
|CLNSRC||ClinVar Unité médicale des maladies autoinflammatoires LabCorp OMIM Allelic Variant|
|CLNACC||RCV000083741.1, RCV000002656.2, RCV000030180.1,|
[PMID 9668175] Non-founder mutations in the MEFV gene establish this gene as the cause of familial Mediterranean fever (FMF).