Rs1038304
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs1038304 |
| hapmap | rs1038304 |
| hgdp | rs1038304 |
| ensembl | rs1038304 |
| gopubmed | rs1038304 |
| scholar | rs1038304 |
| rs1038304 | |
| pharmgkb | rs1038304 |
| hgvbaseg2p | rs1038304 |
| medrefsnp | rs1038304 |
| 23andMe | rs1038304 |
| SNP Nexus |
| Gene | C6orf97 |
| Chromosome | 6 |
| Orientation | plus |
| Position | 151974867 |
| Genotype | Effect |
|---|---|
| rs1038304(A;A)* | ? |
| rs1038304(A;G) | |
| rs1038304(G;G)* | ? |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs1038304(A;G) | 00 |
| Rs1038304 | |
|---|---|
| PubMed | [PMID 18445777] |
| Affy Probeset | SNP_A-1988119 |
| Affy Orientation | same |
| On GW 5.0 | |
| Alleles A/B | A/G |
| Ancestral | G |
| Population | Caucasian |
| Allele | G |
| Case Freq. | |
| Control Freq. | |
| Odds Ratio Het | |
| Odds Ratio Hom | |
| Odds Ratio All | - |
| Disease | Bone mineral density, lower (BMD-L) |
| ? | (A;A) (A;G) (G;G) |
|---|---|
|
| |
rs1038304 increases susceptibility to Bone mineral density variations, lower for carriers of the G allele [PMID 18445777]
| GWAS | |
|---|---|
| SNP | rs1038304 |
| PubMedID | [PMID 18445777] |
| Condition | Bone mineral density (hip) |
| Gene | ESR1 |
| Risk Allele | G |
| pValue | 5.00E-009 |
| OR | 0.08 |
| 95% CI | 0.06-0.11) SD decreas |
| GWAS snp | |
|---|---|
| PMID | [PMID 19079262] |
| Trait | Bone mineral density (hip) |
| Title | New sequence variants associated with bone mineral density |
| Risk Allele | G |
| P-val | 4E-10 |
| Odds Ratio | 0.08 [0.06-0.11] SD decrease |
Related to BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 11; BMND11
according to omim 612114. See also
| PharmGKB | PA162356555 |
| Name | |
| Annotation | GWAS Results: Multiple Genetic Loci for Bone Mineral Density and Fractures (Initial Sample Size: 5,861 individuals; Replication Sample Size: 7,925 individuals; Risk Allele: rs1038304-G). This variant is associated with Bone mineral density (hip). |
| Gene | C6orf97 |
| Featue | |
| Evidence | PubMed ID:18445777; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Bone Diseases, Bone Diseases, Metabolic, Fractures, Bone |
| Curation Level | Non-Curated |
