Rs1018381

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is asnp
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dbSNPrs1018381
nextbiors1018381
hapmaprs1018381
1000 genomesrs1018381
hgdprs1018381
ensemblrs1018381
gopubmedrs1018381
scholarrs1018381
googlers1018381
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openSNPrs1018381
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SNP Nexus

SNPshotrs1018381
SNPdbers1018381
MSV3drs1018381
GeneDTNBP1
Chromosome6
Orientationminus
Position15657070
ReferenceGRCh37 37.1/131
Max Magnitude2
Geno Mag Summary
(C;C) 0
(T;T) 2 impaired cognitive ability
Make rs1018381(C;T)
? (C;C) (C;T) (T;T) 28

g2b2mh blog In a population of healthy individuals, those that carry common variants (such as rs760761, rs1018381, rs2619522) located in the dysbindin (DTNBP1) gene, a risk factor for schizophrenia, show minor cognitive impairments such as decreased attentional capacity, worse performance on memory tasks, and alterations in schizotypal beliefs and experiences.


[PMID 19335929] Association of the DTNBP1 genotype with cognition and personality traits in healthy subjects.


[PMID 19497374] Genetic variation in schizophrenia-risk-gene dysbindin 1 modulates brain activation in anterior cingulate cortex and right temporal gyrus during language production in healthy individuals


[PMID 19077176] Variation in the dysbindin gene and normal cognitive function in three independent population samples

OMIM607145
DescDYSTROBREVIN-BINDING PROTEIN 1; DTNBP1
Variant
Relatedalso

[PMID 19621369] The impact of dystrobrevin-binding protein 1 (DTNBP1) on neural correlates of episodic memory encoding and retrieval

[PMID 19650139] Impact of schizophrenia-risk gene dysbindin 1 on brain activation in bilateral middle frontal gyrus during a working memory task in healthy individuals


[PMID 20846375] The effects of a DTNBP1 gene variant on attention networks: an fMRI study

[PMID 21130223] Meta-Analysis of Genetic Variation in DTNBP1 and General Cognitive Ability

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