Rs10116277

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Orientationplus
is asnp
is mentioned by
dbSNPrs10116277
PheGenIrs10116277
nextbiors10116277
hapmaprs10116277
1000 genomesrs10116277
hgdprs10116277
ensemblrs10116277
gopubmedrs10116277
geneviewrs10116277
scholarrs10116277
googlers10116277
pharmgkbrs10116277
gwascentralrs10116277
openSNPrs10116277
23andMers10116277
23andMe allrs10116277
SNP Nexus

SNPshotrs10116277
SNPdbers10116277
MSV3drs10116277
GeneCDKN2B-AS1
Chromosome9
Orientationplus
GMAF0.3466
Position22081398
ReferenceGRCh38 38.1/141
Max Magnitude
Geno Mag Summary
(G;T)
Make rs10116277(G;G)
Make rs10116277(T;T)
? (G;G) (G;T) (T;T) 28
discussed in this blog postA region of chromosome 9p21 has revealed numerous SNPs correlated with risk of myocardial infarction in a study of 2,000+ patients. This SNP, rs10116277, is highly correlated (r2=0.9) with rs2383207, as well as rs1333040 (r2=0.67). Ultimately, though, the SNP in this study (and region) with the highest disease correlation is rs10757278.

According to a DeCode report, the G allele of his SNP is associated with lower risk of abdominal aortic aneurysm (AAA). [PMID 18176561]

Neighborrs1333040
Distance2007
Neighborrs6475606
Distance453
OMIM611139
Desc
Variant
Relatedalso
[PMID 21375403OA-icon.png] The Relationship Between Polymorphisms on Chromosome 9p21 and Age of Onset of Coronary Heart Disease in Black and White Women


[PMID 18362232OA-icon.png] Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease.


[PMID 18620593OA-icon.png] Investigation of 89 candidate gene variants for effects on all-cause mortality following acute coronary syndrome.


[PMID 18704761OA-icon.png] Molecular genetics of myocardial infarction.


[PMID 18987759OA-icon.png] Genetic testing for atherosclerosis risk: inevitability or pipe dream?


[PMID 19463184OA-icon.png] Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease.


[PMID 19819472OA-icon.png] Common genetic variants on chromosome 9p21 predict perioperative myocardial injury after coronary artery bypass graft surgery.


[PMID 19888323OA-icon.png] Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.


[PMID 20386740OA-icon.png] Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.


[PMID 20718794] Association of polymorphisms in 9p21 region with CAD in North Indian population: replication of SNPs identified through GWAS.