From SNPedia
| Geno
|
Mag
|
Summary
|
| (C;C)
|
0
|
normal risk
|
| (C;T)
|
1.4
|
0.71x lower risk for spondylitis
|
| (T;T)
|
1.7
|
0.71x lower risk for spondylitis
|
| ? | (C;C) (C;T) (T;T) | 28 |
|---|
 |
is one of several SNPs in the
ERAP1 gene that has been shown in a large (over 1,000 Caucasian patients) study to be associated with
ankylosing spondylitis. The odds ratio is 0.71 (p=7.7x10e-9).[
PMID 17952073,
PMID 18037607]
[PMID 19404951] Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis
[PMID 20032103] Association of ARTS1 Gene Polymorphisms with Ankylosing Spondylitis in the Hungarian Population: The rs27044 Variant Is Associated with HLA-B*2705 Subtype in Hungarian Patients with Ankylosing Spondylitis
[PMID 19414429] ARTS1 polymorphisms are associated with ankylosing spondylitis in Koreans
