Rs10050860
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs10050860 |
| hapmap | rs10050860 |
| hgdp | rs10050860 |
| ensembl | rs10050860 |
| gopubmed | rs10050860 |
| scholar | rs10050860 |
| rs10050860 | |
| pharmgkb | rs10050860 |
| hgvbaseg2p | rs10050860 |
| medrefsnp | rs10050860 |
| 23andMe | rs10050860 |
| SNP Nexus |
| Gene | ARTS1 |
| Chromosome | 5 |
| Orientation | plus |
| Position | 96147965 |
| Genotype | Effect |
|---|---|
| rs10050860(T;T) | 0.71x lower risk for spondylitis |
| rs10050860(C;T) | 0.71x lower risk for spondylitis |
| rs10050860(C;C) | normal risk |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs10050860(C;C) | 00 | normal risk |
| Rs10050860(C;T) | 0.71x lower risk for spondylitis | |
| Rs10050860(T;T) | 0.71x lower risk for spondylitis |
rs10050860 is one of several SNPs in the ARTS1 gene that has been shown in a large (over 1,000 Caucasian patients) study to be associated with ankylosing spondylitis. The odds ratio is 0.71 (p=7.7x10e-9).[PMID 17952073, PMID 18037607]
| ? | (C;C) (C;T) (T;T) |
|---|---|
|
| |
[PMID 19404951] Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis
[PMID 20032103] Association of ARTS1 Gene Polymorphisms with Ankylosing Spondylitis in the Hungarian Population: The rs27044 Variant Is Associated with HLA-B*2705 Subtype in Hungarian Patients with Ankylosing Spondylitis
