CASP8
From SNPedia
| is a | gene |
| is | mentioned by |
| wikipedia | CASP8 |
| CASP8 | |
| gopubmed | CASP8 |
| 23andMe | CASP8 |
dbSNP 841
PubMed 841
SADR 841
HugeNav 841
HEFalMp CASP8
| Chromosome position | Summary | |
|---|---|---|
| Rs1045485 | 201857834201,857,834 | |
| Rs17860424 | 201849876201,849,876 | |
| Rs3834129 | 201805777201,805,777 |
[1] A SNP in this gene may reduce the risk of Breast cancer.
rs1045485(C,C) individuals, in this case of European descent, have been reported to be at 40% lower risk of developing breast cancer compared to rs1045485(G,G) individuals [PMID 15601643, PMID 17018785, PMID 17293864]
Another SNP in CASP8, rs17468277, may also affect risk of breast cancer. [PMID 17293864]
[PMID 17450141] the indel (-652 6N del) is associated with multiple cancers
cancergenetics article
